PLPP2

Across TCGA patient cohorts, PLPP2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLPP2-associated genes across cancer lineages are Eosinophils, Hepatocytes, and DC. Each is linked with PLPP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLPP2-to-partner and partner-to-PLPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by PLPP2-low versus PLPP2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP2→partner) and Y-score (partner→PLPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.023	+2.588	.048	.036	3	1
LUSC	Hepatocytes →	+0.010	+3.044	.017	.030	3	1
UCEC	DC →	+0.025	+3.064	.037	.018	3	1
UCEC	GMP →	+0.144	+2.348	<.001	.041	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Eosinophils by PLPP2 expression — LUSC

Explore this box plot interactively →