PLPP1

Across TCGA patient cohorts, PLPP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,702 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PLPP1-associated proteins across cancer lineages are SEPTIN4, MYLK, and ESF1. Each is linked with PLPP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLPP1-to-partner and partner-to-PLPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPP1 versus SEPTIN4 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP1→partner) and Y-score (partner→PLPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEPTIN4 →	+0.616	+0.690	<.001	<.001	3	8
UCEC	MYLK →	+0.812	+0.604	<.001	.002	3	8
UCEC	ESF1 →	-0.361	-0.656	<.001	.004	3	8
OV	GUCY1A1 →	+0.469	+0.651	.004	.004	3	7
CCRCC	GUCY1B1 →	+0.422	+0.918	<.001	<.001	3	7
UCEC	LMOD1_S85 →	+1.066	+0.706	.002	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,702 associations by consensus.

PLPP1 vs SEPTIN4 — OV

Explore this scatter interactively →