PLP2

Across TCGA patient cohorts, PLP2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,354 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLP2-associated genes across cancer lineages are ZSCAN16, REV3L, and HSDL1. Each is linked with PLP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLP2-to-partner and partner-to-PLP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLP2 versus ZSCAN16 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLP2→partner) and Y-score (partner→PLP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZSCAN16 →	-0.692	-0.344	<.001	.003	3	4
GBM	REV3L →	-0.596	-0.425	.004	.003	3	4
LSCC	HSDL1 →	-0.479	-0.343	.004	.002	3	3
CCRCC	CLUHP3 →	-0.879	-0.412	.001	.005	3	3
LSCC	NARS2 →	-0.626	-0.324	.001	<.001	3	3
LSCC	RERE →	-0.348	-0.268	.007	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,354 associations by consensus.

PLP2 vs ZSCAN16 — LSCC

Explore this scatter interactively →