PLOD2

Across TCGA patient cohorts, PLOD2 mutation is significantly associated with the RNA expression of many other genes, with 3,579 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLOD2-associated genes across cancer lineages are RN7SL693P, RN7SKP266, and AGKP1. Each is linked with PLOD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLOD2-to-partner and partner-to-PLOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL693P grouped by PLOD2-low versus PLOD2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLOD2→partner) and Y-score (partner→PLOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL693P →	+0.329	+2.885	<.001	.008	3	3
HNSC	RN7SKP266 →	+0.084	+4.526	<.001	.007	3	3
HNSC	AGKP1 →	+0.130	+4.495	<.001	.002	3	2
HNSC	LINC01758 →	+0.124	+4.025	.003	.004	3	2
HNSC	TRIAP1P1 →	+0.139	+4.754	<.001	.005	3	2
HNSC	RNU7-176P →	+0.529	+4.600	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,579 associations by consensus.

RN7SL693P by PLOD2 expression — LUAD

Explore this box plot interactively →