PLOD1

Across TCGA patient cohorts, PLOD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,318 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLOD1-associated proteins across cancer lineages are PLOD2, BMP1, and CRTAP. Each is linked with PLOD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLOD1-to-partner and partner-to-PLOD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLOD1 versus PLOD2 in PDAC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLOD1→partner) and Y-score (partner→PLOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLOD2 →	+1.071	+0.809	<.001	<.001	3	9
OV	BMP1 →	+0.895	+1.048	<.001	<.001	3	8
BRCA	CRTAP →	+0.524	+0.514	<.001	<.001	3	8
PDAC	ITGA5 →	+0.665	+0.682	<.001	<.001	3	8
BRCA	P3H1 →	+0.767	+1.120	<.001	<.001	3	8
OV	PLAU →	+0.883	+0.995	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,318 associations by consensus.

PLOD1 vs PLOD2 — PDAC

Explore this scatter interactively →