PLN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLN RNA expression is significantly associated with the protein abundance of many other proteins, with 22,257 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLN-associated proteins across cancer lineages are MYH11, ZYX, and TLN1. Each is linked with PLN in more than 9 cancer types. Because this analysis shows association rather than direction, both PLN-to-partner and partner-to-PLN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLN→partner) and Y-score (partner→PLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMYH11 →+1.120+1.067<.001<.001310
UCECZYX →+0.490+1.173<.001<.00139
UCECTLN1 →+0.475+1.197<.001<.00139
OVTLN1_S1641 →+1.134+1.875<.001<.00139
OVTNS1 →+1.257+2.310<.001<.00139
UCECPPP1R12C →+0.494+1.313<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,257 associations by consensus.

Exploration