Across TCGA patient cohorts, PLN protein abundance is significantly associated with the RNA expression of many other genes, with 699 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLN-associated genes across cancer lineages are RNU6-137P, VSIR, and ABCC3. Each is linked with PLN in more than 1 cancer types. Because this analysis shows association rather than direction, both PLN-to-partner and partner-to-PLN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLN→partner) and Y-score (partner→PLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-137P →	+2.592	+1.962	.004	.004	3	2
OV	VSIR →	+1.168	+0.838	.005	.009	3	1
OV	ABCC3 →	+1.096	+0.854	.008	.008	3	1
OV	NCAPG →	-1.065	-0.891	.005	.004	3	1
OV	RMDN2 →	+0.972	+1.265	.008	.001	3	1
OV	PEX16 →	+0.586	+0.956	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 699 associations by consensus.

Exploration

PLN survival (RNA) · tumor vs normal (RNA) · all PLN data types