PLN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLN RNA expression is significantly associated with the go_rna of many other GO terms, with 868 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLN-associated GO terms across cancer lineages are Negative regulation of ATPase-coupled calcium transmembrane transporter activity, Platelet activation, and Regulation of mononuclear cell proliferation. Each is linked with PLN in more than 4 cancer types. Because this analysis shows association rather than direction, both PLN-to-partner and partner-to-PLN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLN→partner) and Y-score (partner→PLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINNegative regulation of ATPase-coupled calcium transmembrane transporter activity →+0.628+1.323<.001.00235
SOFT_TISSUEPlatelet activation →-0.059-0.651.001.00334
OVARYRegulation of mononuclear cell proliferation →-0.079-0.044.002.00534
OVARYNegative regulation of dendritic spine morphogenesis →-0.152-0.059.003.00234
BREASTL-arginine transmembrane transport →-0.092-0.038.002.00834
URINARY_TRACTCell chemotaxis →-0.082-0.044.002.00924
Each partner links to its Q-omics profile. Showing the 6 strongest of 868 associations by consensus.

Exploration