Across TCGA cell cohorts, PLK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,193 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLK5-associated GO terms across cancer lineages are Base-excision repair, gap-filling, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Sperm-egg recognition. Each is linked with PLK5 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLK5-to-partner and partner-to-PLK5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLK5→partner) and Y-score (partner→PLK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Base-excision repair, gap-filling →	+0.083	+0.475	.001	.003	3	7
OVARY	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.123	+0.155	<.001	<.001	3	7
BLOOD_Lymphoma	Sperm-egg recognition →	-0.173	-0.206	<.001	<.001	3	6
BREAST	Blood coagulation, intrinsic pathway →	-0.230	-0.259	.003	.006	3	6
BREAST	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.120	+0.250	.001	.009	3	6
SOFT_TISSUE	Sperm mitochondrial sheath assembly →	-0.193	-0.164	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,193 associations by consensus.

Exploration

PLK5 survival (RNA) · tumor vs normal (RNA) · all PLK5 data types