PLIN3

Across TCGA patient cohorts, PLIN3 mutation is significantly associated with the RNA expression of many other genes, with 938 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLIN3-associated genes across cancer lineages are OR7A17, TRAJ39, and RNU6-1207P. Each is linked with PLIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLIN3-to-partner and partner-to-PLIN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7A17 grouped by PLIN3-low versus PLIN3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN3→partner) and Y-score (partner→PLIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR7A17 →	+0.041	+4.038	<.001	.002	3	2
UCEC	TRAJ39 →	+0.671	+2.330	<.001	<.001	3	2
STAD	RNU6-1207P →	+0.273	+3.562	.002	.007	3	2
UCEC	RNA5SP477 →	+0.901	+2.223	<.001	.003	3	2
UCEC	RNU6-1082P →	+0.229	+2.851	<.001	.003	3	2
UCEC	RNA5SP421 →	+0.901	+2.089	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 938 associations by consensus.

OR7A17 by PLIN3 expression — BLCA

Explore this box plot interactively →