PLIN2

Across TCGA patient cohorts, PLIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,220 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLIN2-associated proteins across cancer lineages are ITGA5, TREM1, and P4HA2. Each is linked with PLIN2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLIN2-to-partner and partner-to-PLIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLIN2 versus ITGA5 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN2→partner) and Y-score (partner→PLIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGA5 →	+0.698	+1.277	<.001	<.001	3	7
PDAC	TREM1 →	+1.347	+1.085	<.001	<.001	3	6
BRCA	P4HA2 →	+0.999	+1.225	<.001	<.001	3	6
GBM	PIK3AP1 →	+0.617	+1.020	<.001	<.001	3	6
GBM	PLG →	+0.642	+1.222	<.001	<.001	3	6
BRCA	PLOD2 →	+1.204	+1.435	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,220 associations by consensus.

PLIN2 vs ITGA5 — OV

Explore this scatter interactively →