PLIN2

Across TCGA cell cohorts, PLIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,448 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLIN2-associated GO terms across cancer lineages are Regulation of triglyceride storage, Positive regulation of triglyceride storage, and PML body organization. Each is linked with PLIN2 in more than 15 cancer types. Because this analysis shows association rather than direction, both PLIN2-to-partner and partner-to-PLIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of triglyceride storage grouped by PLIN2-low versus PLIN2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN2→partner) and Y-score (partner→PLIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of triglyceride storage →	+1.466	+2.376	<.001	<.001	3	16
LUNG_SCLC	Positive regulation of triglyceride storage →	+1.365	+2.376	<.001	<.001	3	16
BONE	PML body organization →	+0.193	+4.242	<.001	<.001	3	9
BREAST	Positive regulation of lipid storage →	+0.145	+2.536	.001	<.001	3	9
BONE	Response to oxygen levels →	+0.068	+3.039	.001	.007	3	7
LUNG_NSCLC_LUSC	Lipid droplet disassembly →	+0.188	+3.501	.009	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,448 associations by consensus.

Regulation of triglyceride storage by PLIN2 expression — LUNG_SCLC

Explore this box plot interactively →