PLIN1

Across TCGA cell cohorts, PLIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,423 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLIN1-associated GO terms across cancer lineages are Fatty acid oxidation, Fatty acid beta-oxidation, and Monocarboxylic acid catabolic process. Each is linked with PLIN1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PLIN1-to-partner and partner-to-PLIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid oxidation grouped by PLIN1-low versus PLIN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN1→partner) and Y-score (partner→PLIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Fatty acid oxidation →	+0.069	+0.307	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Fatty acid beta-oxidation →	+0.103	+0.376	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.060	+0.283	.002	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Lipid oxidation →	+0.090	+0.318	<.001	<.001	3	9
URINARY_TRACT	Flagellated sperm motility →	-0.085	-0.206	.005	.005	3	9
URINARY_TRACT	Sperm motility →	-0.085	-0.206	.005	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,423 associations by consensus.

Fatty acid oxidation by PLIN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →