PLGLA

Across TCGA patient cohorts, PLGLA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,376 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PLGLA-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Positive regulation of DNA repair, and Regulation of DNA repair. Each is linked with PLGLA in more than 12 cancer types. Because this analysis shows association rather than direction, both PLGLA-to-partner and partner-to-PLGLA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by PLGLA-low versus PLGLA-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLGLA→partner) and Y-score (partner→PLGLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.056	+0.114	<.001	<.001	3	13
STAD	Positive regulation of DNA repair →	+0.053	+0.125	<.001	<.001	3	12
STAD	Regulation of DNA repair →	+0.056	+0.105	<.001	<.001	3	12
ESCA	Methylation →	+0.059	+0.208	<.001	.001	3	12
STAD	RNA methylation →	+0.051	+0.107	<.001	<.001	3	12
ESCA	Establishment of protein localization to membrane →	+0.067	+0.235	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,376 associations by consensus.

Positive regulation of DNA metabolic process by PLGLA expression — STAD

Explore this box plot interactively →