PLG

Across TCGA patient cohorts, PLG RNA expression is significantly associated with the protein abundance of many other proteins, with 11,213 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLG-associated proteins across cancer lineages are TPPP, MAP3K20_S727, and MYL6B. Each is linked with PLG in more than 2 cancer types. Because this analysis shows association rather than direction, both PLG-to-partner and partner-to-PLG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLG versus TPPP in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLG→partner) and Y-score (partner→PLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPPP →	+0.919	+0.167	<.001	<.001	3	3
GBM	MAP3K20_S727 →	-0.721	-0.189	<.001	<.001	3	3
COAD	MYL6B →	+0.442	+0.028	<.001	<.001	3	3
GBM	DMTN_S156 →	+0.545	+0.137	.001	.001	3	3
UCEC	WDR19 →	+0.344	+0.668	<.001	<.001	3	3
CCRCC	PEBP1 →	+0.432	+2.132	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,213 associations by consensus.

PLG vs TPPP — GBM

Explore this scatter interactively →