PLG

Across TCGA patient cohorts, PLG protein abundance is significantly associated with the RNA expression of many other genes, with 13,165 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLG-associated genes across cancer lineages are SLC2A3, SERPINE1, and IL6. Each is linked with PLG in more than 8 cancer types. Because this analysis shows association rather than direction, both PLG-to-partner and partner-to-PLG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLG versus SLC2A3 in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLG→partner) and Y-score (partner→PLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC2A3 →	+1.536	+0.583	<.001	<.001	3	9
COAD	SERPINE1 →	+1.565	+0.695	<.001	<.001	3	8
LUAD	IL6 →	+1.969	+0.625	<.001	<.001	3	8
COAD	CD93 →	+0.766	+0.670	.004	<.001	3	7
OV	VEGFC →	+0.938	+0.768	<.001	<.001	3	7
COAD	ITGA5 →	+1.057	+0.572	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,165 associations by consensus.

PLG vs SLC2A3 — LUAD

Explore this scatter interactively →