Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, PLEKHN1 mutation is significantly associated with the RNA expression of many other genes, with 598 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible PLEKHN1-associated genes across cancer lineages are LINC00351, NUS1P3, and OR9A1P. Each is linked with PLEKHN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLEKHN1-to-partner and partner-to-PLEKHN1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (PLEKHN1→partner) and Y-score (partner→PLEKHN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.