Across TCGA cell cohorts, PLEKHN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,707 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLEKHN1-associated GO terms across cancer lineages are Fibroblast migration, Negative regulation of immune response, and Plasma membrane organization. Each is linked with PLEKHN1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PLEKHN1-to-partner and partner-to-PLEKHN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHN1→partner) and Y-score (partner→PLEKHN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Fibroblast migration →	+0.211	+0.842	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Negative regulation of immune response →	+0.077	+1.053	<.001	<.001	3	15
BONE	Plasma membrane organization →	+0.158	+0.696	<.001	<.001	3	14
BONE	Assembly of actomyosin apparatus involved in cytokinesis →	+0.223	+0.901	<.001	.001	3	14
BONE	Actomyosin contractile ring assembly →	+0.223	+0.901	<.001	.001	3	14
BONE	Canonical NF-kappaB signal transduction →	+0.125	+0.869	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

Exploration

PLEKHN1 survival (RNA) · tumor vs normal (RNA) · all PLEKHN1 data types