PLEKHJ1

Across TCGA patient cohorts, PLEKHJ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,152 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLEKHJ1-associated proteins across cancer lineages are SGTA, PCF11, and ZFP36L1_S54. Each is linked with PLEKHJ1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLEKHJ1-to-partner and partner-to-PLEKHJ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHJ1 versus SGTA in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHJ1→partner) and Y-score (partner→PLEKHJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SGTA →	+0.251	+0.470	<.001	<.001	3	6
GBM	PCF11 →	+0.270	+0.322	<.001	.002	3	4
GBM	ZFP36L1_S54 →	-0.548	-0.301	.001	.003	3	4
GBM	ZNF326 →	+0.394	+0.358	<.001	<.001	3	4
LSCC	NCAPG →	+0.653	+0.480	<.001	<.001	3	4
GBM	CHAF1A_S141 →	+0.763	+0.430	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,152 associations by consensus.

PLEKHJ1 vs SGTA — LSCC

Explore this scatter interactively →