PLEKHH1

Across TCGA patient cohorts, PLEKHH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,574 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLEKHH1-associated proteins across cancer lineages are MIA3_S727, MSN, and DDAH1. Each is linked with PLEKHH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLEKHH1-to-partner and partner-to-PLEKHH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHH1 versus MIA3_S727 in CCRCC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHH1→partner) and Y-score (partner→PLEKHH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MIA3_S727 →	-0.543	-0.500	.001	.003	3	5
GBM	MSN →	-0.550	-0.966	<.001	<.001	3	5
GBM	DDAH1 →	+0.606	+1.382	<.001	<.001	3	5
HNSC	RPS2_S264 →	-0.694	-0.693	.004	<.001	3	4
GBM	RPS6KA5 →	+0.482	+0.944	<.001	<.001	3	4
GBM	RRBP1 →	-0.522	-1.070	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,574 associations by consensus.

PLEKHH1 vs MIA3_S727 — CCRCC

Explore this scatter interactively →