PLEKHH1

Across TCGA cell cohorts, PLEKHH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,142 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PLEKHH1-associated GO terms across cancer lineages are Glycerophospholipid biosynthetic process, Phospholipid biosynthetic process, and Glycerophospholipid metabolic process. Each is linked with PLEKHH1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PLEKHH1-to-partner and partner-to-PLEKHH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerophospholipid biosynthetic process grouped by PLEKHH1-low versus PLEKHH1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHH1→partner) and Y-score (partner→PLEKHH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Glycerophospholipid biosynthetic process →	+0.054	+1.724	<.001	<.001	3	13
URINARY_TRACT	Phospholipid biosynthetic process →	+0.050	+2.051	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.047	+1.376	<.001	<.001	3	12
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.056	+1.654	<.001	.001	3	12
CNS	Angiogenesis →	-0.066	-0.834	<.001	.002	3	11
SOFT_TISSUE	Positive regulation of calcium ion transport →	-0.106	-1.266	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,142 associations by consensus.

Glycerophospholipid biosynthetic process by PLEKHH1 expression — URINARY_TRACT

Explore this box plot interactively →