PLEKHG1

Across TCGA cell cohorts, PLEKHG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,272 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLEKHG1-associated GO terms across cancer lineages are Purine ribonucleoside metabolic process, Negative regulation of stem cell differentiation, and Protein transport within lipid bilayer. Each is linked with PLEKHG1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLEKHG1-to-partner and partner-to-PLEKHG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleoside metabolic process grouped by PLEKHG1-low versus PLEKHG1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG1→partner) and Y-score (partner→PLEKHG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Purine ribonucleoside metabolic process →	-0.151	-1.457	<.001	.001	3	10
OVARY	Negative regulation of stem cell differentiation →	+0.175	+1.963	<.001	<.001	3	8
BLOOD_Lymphoma	Protein transport within lipid bilayer →	+0.277	+2.405	.004	<.001	3	8
LIVER	Positive regulation of myoblast differentiation →	+0.142	+2.137	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Cytotoxic T cell degranulation →	+0.304	+1.344	.004	.009	3	8
URINARY_TRACT	Serotonin secretion →	+1.309	+1.339	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,272 associations by consensus.

Purine ribonucleoside metabolic process by PLEKHG1 expression — STOMACH

Explore this box plot interactively →