PLEKHA2

Across TCGA patient cohorts, PLEKHA2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLEKHA2-associated genes across cancer lineages are Myocytes and Th2 cells. Each is linked with PLEKHA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLEKHA2-to-partner and partner-to-PLEKHA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myocytes grouped by PLEKHA2-low versus PLEKHA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA2→partner) and Y-score (partner→PLEKHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myocytes →	+0.052	+3.212	.003	.010	3	1
UCEC	Th2 cells →	+0.236	+3.169	.017	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Myocytes by PLEKHA2 expression — UCEC

Explore this box plot interactively →