PLD3

Across TCGA patient cohorts, PLD3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,535 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLD3-associated genes across cancer lineages are STX11, PLA2G7, and CCR1. Each is linked with PLD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLD3-to-partner and partner-to-PLD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLD3 versus STX11 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLD3→partner) and Y-score (partner→PLD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STX11 →	+0.812	+0.426	<.001	<.001	3	8
CCRCC	PLA2G7 →	+1.000	+0.346	<.001	<.001	3	8
HNSC	CCR1 →	+1.048	+0.367	<.001	.001	3	8
CCRCC	CTSZ →	+0.874	+0.482	<.001	<.001	3	7
BRCA	TLR8 →	+0.805	+0.463	<.001	<.001	3	7
PDAC	CD37 →	+0.616	+0.494	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,535 associations by consensus.

PLD3 vs STX11 — HNSC

Explore this scatter interactively →