PLD2

Across TCGA cell cohorts, PLD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,912 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PLD2-associated GO terms across cancer lineages are Regulation of translation at synapse, modulating synaptic transmission, Retrograde transport, endosome to Golgi, and Negative regulation of calcium ion export across plasma membrane. Each is linked with PLD2 in more than 14 cancer types. Because this analysis shows association rather than direction, both PLD2-to-partner and partner-to-PLD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at synapse, modulating synaptic transmission grouped by PLD2-low versus PLD2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLD2→partner) and Y-score (partner→PLD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of translation at synapse, modulating synaptic transmission →	+0.123	+0.686	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.094	+1.565	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.085	+1.334	<.001	<.001	3	14
STOMACH	Endosomal transport →	+0.070	+1.064	.003	.009	3	14
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.103	+1.664	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.098	+1.277	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,912 associations by consensus.

Regulation of translation at synapse, modulating synaptic transmission by PLD2 expression — PANCREAS

Explore this box plot interactively →