PLCXD2

Across TCGA cell cohorts, PLCXD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,846 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLCXD2-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of protein modification by small protein conjugation or removal, and IRE1-mediated unfolded protein response. Each is linked with PLCXD2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLCXD2-to-partner and partner-to-PLCXD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by PLCXD2-low versus PLCXD2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCXD2→partner) and Y-score (partner→PLCXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of post-translational protein modification →	+0.045	+0.431	<.001	<.001	3	9
BLOOD_Lymphoma	Regulation of protein modification by small protein conjugation or removal →	+0.057	+0.807	<.001	<.001	3	9
SOFT_TISSUE	IRE1-mediated unfolded protein response →	+0.141	+1.473	<.001	.001	3	9
OESOPHAGUS	Spliceosomal tri-snRNP complex assembly →	+0.114	+2.014	.002	<.001	3	8
KIDNEY	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.190	+2.811	.001	<.001	3	8
LUNG_SCLC	Xenobiotic catabolic process →	-0.173	-1.547	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,846 associations by consensus.

Regulation of post-translational protein modification by PLCXD2 expression — BLOOD_Lymphoma

Explore this box plot interactively →