PLCXD1

Across TCGA patient cohorts, PLCXD1 protein abundance is significantly associated with the RNA expression of many other genes, with 193 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLCXD1-associated genes across cancer lineages are MGRN1, SUFU, and PIGL. Each is linked with PLCXD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLCXD1-to-partner and partner-to-PLCXD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCXD1 versus MGRN1 in HNSC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCXD1→partner) and Y-score (partner→PLCXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MGRN1 →	+0.519	+1.008	.004	.001	3	1
HNSC	SUFU →	+0.683	+0.866	.001	.009	3	1
HNSC	PIGL →	+0.746	+0.987	.007	.001	3	1
HNSC	UPK2 →	+0.553	+0.987	<.001	.001	3	1
HNSC	ST8SIA1 →	+0.956	+0.891	.001	.007	3	1
HNSC	OCM →	+0.317	+0.585	.009	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

PLCXD1 vs MGRN1 — HNSC

Explore this scatter interactively →