PLCXD1

Across TCGA patient cohorts, PLCXD1 protein abundance is significantly associated with the protein abundance of many other proteins, with 133 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLCXD1-associated proteins across cancer lineages are KMT2A_S3511, MED13L, and APOL3_S315. Each is linked with PLCXD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLCXD1-to-partner and partner-to-PLCXD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCXD1 versus KMT2A_S3511 in HNSC, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCXD1→partner) and Y-score (partner→PLCXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KMT2A_S3511 →	+0.804	+1.157	.001	.005	3	1
HNSC	MED13L →	+1.022	+1.357	.002	.004	3	1
HNSC	APOL3_S315 →	+1.061	+1.511	.001	.003	3	1
HNSC	BCR_S459 →	+1.747	+1.347	.001	.004	3	1
HNSC	TPSAB1 →	+1.556	+1.491	<.001	.004	3	1
HNSC	USP28_S1053 →	+0.967	+1.357	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

PLCXD1 vs KMT2A_S3511 — HNSC

Explore this scatter interactively →