PLCXD1

Across TCGA patient cohorts, PLCXD1 mutation is significantly associated with the RNA expression of many other genes, with 1,929 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLCXD1-associated genes across cancer lineages are OR13C3, IL21, and RNU7-149P. Each is linked with PLCXD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLCXD1-to-partner and partner-to-PLCXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C3 grouped by PLCXD1-low versus PLCXD1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCXD1→partner) and Y-score (partner→PLCXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	OR13C3 →	+0.066	+5.544	<.001	.004	3	2
UCEC	IL21 →	+0.165	+1.874	<.001	.005	3	2
SKCM	RNU7-149P →	+0.515	+4.771	<.001	.006	3	2
SKCM	MIR3115 →	+0.663	+4.680	<.001	.007	3	2
UCEC	MIR6803 →	+0.144	+4.390	<.001	.003	3	2
LUAD	MIR1269A →	+0.300	+5.798	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,929 associations by consensus.

OR13C3 by PLCXD1 expression — LIHC

Explore this box plot interactively →