PLCXD1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PLCXD1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PLCXD1-associated genes across cancer lineages are KRTAP11-1. Each is linked with PLCXD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLCXD1-to-partner and partner-to-PLCXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP11-1 grouped by PLCXD1-low versus PLCXD1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCXD1→partner) and Y-score (partner→PLCXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYKRTAP11-1 →+0.139+5.807<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

KRTAP11-1 by PLCXD1 expression — OVARY

Box plot of KRTAP11-1 in PLCXD1-low vs PLCXD1-high samples in OVARY.

Explore this box plot interactively →

Exploration