PLCL2

Across TCGA cell cohorts, PLCL2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLCL2-associated genes across cancer lineages are MDFIC, E2F7, and USP1. Each is linked with PLCL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLCL2-to-partner and partner-to-PLCL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCL2 versus MDFIC in LARGE_INTESTINE, with a Pearson correlation of 0.41.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCL2→partner) and Y-score (partner→PLCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MDFIC →	+1.557	+0.903	<.001	<.001	3	6
LIVER	E2F7 →	+1.350	+1.038	.001	.007	1	8
URINARY_TRACT	USP1 →	+1.045	+1.748	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	RFC1 →	+0.975	+0.563	.004	.002	2	7
OVARY	SH3RF1 →	+1.308	+1.035	<.001	<.001	3	6
URINARY_TRACT	RBPJ →	+1.168	+2.214	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,127 associations by consensus.

PLCL2 vs MDFIC — LARGE_INTESTINE

Explore this scatter interactively →