PLCL2

Across TCGA cell cohorts, PLCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,275 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLCL2-associated GO terms across cancer lineages are DNA damage tolerance, Mitotic sister chromatid segregation, and Mitotic nuclear division. Each is linked with PLCL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLCL2-to-partner and partner-to-PLCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA damage tolerance grouped by PLCL2-low versus PLCL2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCL2→partner) and Y-score (partner→PLCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA damage tolerance →	+0.048	+1.341	.001	<.001	3	10
OVARY	Mitotic sister chromatid segregation →	+0.078	+0.767	<.001	.007	3	9
OVARY	Mitotic nuclear division →	+0.077	+1.052	<.001	<.001	3	8
BLOOD_Leukemia	Negative regulation of cell cycle phase transition →	+0.049	+1.037	<.001	.003	3	8
STOMACH	Nuclear division →	+0.063	+1.407	<.001	<.001	3	8
STOMACH	Kinetochore organization →	+0.081	+1.453	.005	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,275 associations by consensus.

DNA damage tolerance by PLCL2 expression — BLOOD_Lymphoma

Explore this box plot interactively →