PLCL1

Across TCGA patient cohorts, PLCL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLCL1-associated proteins across cancer lineages are PLCL1_S569, PLCL1_T556, and PRKG1. Each is linked with PLCL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLCL1-to-partner and partner-to-PLCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCL1 versus PLCL1_S569 in BRCA, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCL1→partner) and Y-score (partner→PLCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLCL1_S569 →	+1.018	+1.458	<.001	<.001	3	10
GBM	PLCL1_T556 →	+0.964	+1.453	<.001	<.001	3	9
UCEC	PRKG1 →	+0.889	+0.708	<.001	.001	3	9
COAD	FERMT2 →	+0.742	+0.548	<.001	<.001	3	9
OV	PLAC9 →	+1.159	+0.579	<.001	.003	3	8
UCEC	SORBS3 →	+0.685	+0.658	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,878 associations by consensus.

PLCL1 vs PLCL1_S569 — BRCA

Explore this scatter interactively →