PLCH2

Across TCGA patient cohorts, PLCH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,358 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLCH2-associated proteins across cancer lineages are PLCH2_S487, PLCH2_S491, and ADIRF. Each is linked with PLCH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLCH2-to-partner and partner-to-PLCH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCH2 versus PLCH2_S487 in LSCC, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCH2→partner) and Y-score (partner→PLCH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLCH2_S487 →	+1.561	+1.401	<.001	<.001	3	6
LSCC	PLCH2_S491 →	+1.561	+1.401	<.001	<.001	3	6
GBM	ADIRF →	+0.925	+0.804	<.001	<.001	3	5
LSCC	PLCH2_S595 →	+1.322	+1.216	<.001	<.001	3	5
BRCA	MKI67_S827 →	-0.805	-0.857	.007	.002	3	4
LSCC	BAZ1B →	-0.333	-0.827	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,358 associations by consensus.

PLCH2 vs PLCH2_S487 — LSCC

Explore this scatter interactively →