PLCH1

Across TCGA patient cohorts, PLCH1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,598 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLCH1-associated genes across cancer lineages are AP4S1, VIPR2, and FXYD6. Each is linked with PLCH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLCH1-to-partner and partner-to-PLCH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCH1 versus AP4S1 in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCH1→partner) and Y-score (partner→PLCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AP4S1 →	-0.444	-0.586	<.001	<.001	3	4
GBM	VIPR2 →	-1.947	-0.540	<.001	<.001	3	4
CCRCC	FXYD6 →	-1.053	-0.504	<.001	<.001	3	4
BRCA	GNPDA2 →	-0.644	-0.484	<.001	.001	3	4
UCEC	RPP14 →	-0.362	-0.217	<.001	<.001	3	4
BRCA	APBB2 →	-0.876	-0.579	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,598 associations by consensus.

PLCH1 vs AP4S1 — BRCA

Explore this scatter interactively →