PLCH1

Across TCGA cell cohorts, PLCH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,826 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLCH1-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Hormone transport, and Amino acid metabolic process. Each is linked with PLCH1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLCH1-to-partner and partner-to-PLCH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by PLCH1-low versus PLCH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCH1→partner) and Y-score (partner→PLCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peptidyl-lysine oxidation →	-1.639	-1.349	<.001	<.001	3	10
LIVER	Hormone transport →	-0.147	-1.195	.003	<.001	3	10
LUNG_NSCLC_LUSC	Amino acid metabolic process →	+0.060	+0.841	.004	.009	3	10
BONE	Muscle organ development →	-0.128	-1.174	<.001	<.001	3	10
BONE	Detoxification of copper ion →	-0.320	-1.291	<.001	<.001	3	9
KIDNEY	Luteinization →	-1.385	-1.083	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,826 associations by consensus.

Peptidyl-lysine oxidation by PLCH1 expression — BONE

Explore this box plot interactively →