PLCE1P1

Across TCGA patient cohorts, PLCE1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 594 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible PLCE1P1-associated GO terms across cancer lineages are Cardiolipin biosynthetic process, Epigenetic regulation of gene expression, and Convergent extension involved in gastrulation. Each is linked with PLCE1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLCE1P1-to-partner and partner-to-PLCE1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiolipin biosynthetic process grouped by PLCE1P1-low versus PLCE1P1-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCE1P1→partner) and Y-score (partner→PLCE1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Cardiolipin biosynthetic process →	+0.055	+0.007	.002	.003	3	2
LUSC	Epigenetic regulation of gene expression →	+0.062	+0.054	<.001	.004	3	2
LUSC	Convergent extension involved in gastrulation →	+0.081	+0.058	<.001	.005	3	1
LUSC	Cell surface receptor signaling pathway involved in heart development →	+0.075	+0.092	<.001	.004	3	1
LUSC	Meiosis I cell cycle process →	+0.037	+0.150	<.001	<.001	3	1
KIRC	Regulation of membrane lipid distribution →	+0.035	+0.005	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 594 associations by consensus.

Cardiolipin biosynthetic process by PLCE1P1 expression — KIRC

Explore this box plot interactively →