PLCD3

Across TCGA patient cohorts, PLCD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,587 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLCD3-associated proteins across cancer lineages are AHNAK2, PLCD3_S489, and PLCD3_S496. Each is linked with PLCD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLCD3-to-partner and partner-to-PLCD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCD3 versus AHNAK2 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCD3→partner) and Y-score (partner→PLCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AHNAK2 →	+0.924	+0.660	<.001	.001	3	7
BRCA	PLCD3_S489 →	+0.902	+0.990	<.001	<.001	3	7
OV	PLCD3_S496 →	+1.232	+1.261	<.001	<.001	3	7
CCRCC	AHNAK2_S260 →	+1.525	+0.795	<.001	<.001	3	6
LSCC	S100A16 →	+0.644	+0.644	<.001	.001	3	5
LSCC	IL1RN →	+1.249	+0.816	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,587 associations by consensus.

PLCD3 vs AHNAK2 — LSCC

Explore this scatter interactively →