PLCD3

Across TCGA patient cohorts, PLCD3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,077 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLCD3-associated genes across cancer lineages are STON2, GALNT15, and HTRA1. Each is linked with PLCD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLCD3-to-partner and partner-to-PLCD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCD3 versus STON2 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCD3→partner) and Y-score (partner→PLCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STON2 →	+0.940	+0.495	<.001	.001	3	5
GBM	GALNT15 →	+0.966	+0.345	<.001	<.001	3	5
HNSC	HTRA1 →	+1.200	+0.467	<.001	<.001	3	5
BRCA	PHLDA3 →	+0.826	+0.363	<.001	<.001	3	5
GBM	FEZ1 →	+0.651	+0.418	<.001	.001	3	5
HNSC	CRYAB →	+1.348	+0.251	<.001	.007	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,077 associations by consensus.

PLCD3 vs STON2 — GBM

Explore this scatter interactively →