PLCB4

Across TCGA patient cohorts, PLCB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,154 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLCB4-associated proteins across cancer lineages are STRBP, TRIM2, and MYEF2. Each is linked with PLCB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLCB4-to-partner and partner-to-PLCB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCB4 versus STRBP in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCB4→partner) and Y-score (partner→PLCB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STRBP →	+0.562	+1.531	<.001	<.001	3	6
HNSC	TRIM2 →	+0.587	+1.262	<.001	<.001	3	6
HNSC	MYEF2 →	+0.842	+1.189	<.001	<.001	3	5
LUAD	RNF213 →	-0.305	-0.854	.001	.001	3	4
OV	S100A14 →	-1.077	-0.860	.001	.006	3	4
LSCC	S100A16 →	-0.591	-1.190	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,154 associations by consensus.

PLCB4 vs STRBP — HNSC

Explore this scatter interactively →