PLCB4

Across TCGA cell cohorts, PLCB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,636 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLCB4-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Regulation of angiotensin-activated signaling pathway, and Regulation of glutamate uptake involved in transmission of nerve impulse. Each is linked with PLCB4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLCB4-to-partner and partner-to-PLCB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by PLCB4-low versus PLCB4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCB4→partner) and Y-score (partner→PLCB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Peptidyl-lysine oxidation →	+1.127	+1.972	.001	.002	3	8
CNS	Regulation of angiotensin-activated signaling pathway →	+0.132	+1.829	<.001	<.001	3	7
OVARY	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.149	+2.848	<.001	<.001	3	7
BONE	Glycosaminoglycan catabolic process →	+0.194	+2.436	.004	.001	3	7
SOFT_TISSUE	Response to interleukin-9 →	+0.233	+1.934	<.001	<.001	3	7
URINARY_TRACT	Positive regulation of focal adhesion assembly →	+0.132	+2.689	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,636 associations by consensus.

Peptidyl-lysine oxidation by PLCB4 expression — URINARY_TRACT

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