PLCB3

Across TCGA patient cohorts, PLCB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,361 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PLCB3-associated proteins across cancer lineages are PDIA5, PLCB3_S537, and PLCB3_S926. Each is linked with PLCB3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLCB3-to-partner and partner-to-PLCB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCB3 versus PDIA5 in HNSC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCB3→partner) and Y-score (partner→PLCB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PDIA5 →	-0.415	-0.888	<.001	<.001	3	4
GBM	PLCB3_S537 →	+0.524	+0.369	<.001	<.001	3	4
LSCC	PLCB3_S926 →	+0.733	+0.689	<.001	<.001	3	4
BRCA	CCDC91 →	-0.384	-0.547	<.001	<.001	3	4
CCRCC	CRELD2 →	-0.541	-0.236	.007	.007	3	4
LSCC	ARAF →	-0.133	-0.378	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,361 associations by consensus.

PLCB3 vs PDIA5 — HNSC

Explore this scatter interactively →