PLBD2

Across TCGA patient cohorts, PLBD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,817 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLBD2-associated proteins across cancer lineages are THBS2, MXRA7, and VCAN_S1349. Each is linked with PLBD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLBD2-to-partner and partner-to-PLBD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLBD2 versus THBS2 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLBD2→partner) and Y-score (partner→PLBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	THBS2 →	+0.983	+0.534	<.001	<.001	3	5
BRCA	MXRA7 →	+0.645	+0.522	<.001	<.001	3	4
OV	VCAN_S1349 →	+1.263	+1.214	<.001	<.001	3	4
PDAC	VIM_S214 →	+0.565	+0.511	.002	<.001	3	4
PDAC	WWP2 →	-0.259	-0.424	.005	.001	3	4
OV	OLFML2B →	+0.747	+0.920	.008	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,817 associations by consensus.

PLBD2 vs THBS2 — BRCA

Explore this scatter interactively →