PLBD2

Across TCGA patient cohorts, PLBD2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,682 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLBD2-associated genes across cancer lineages are TLR8, EMB, and IL21R. Each is linked with PLBD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLBD2-to-partner and partner-to-PLBD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLBD2 versus TLR8 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLBD2→partner) and Y-score (partner→PLBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TLR8 →	+1.140	+0.334	<.001	.003	3	5
COAD	EMB →	+1.077	+0.294	<.001	.004	3	5
UCEC	IL21R →	+1.045	+0.367	<.001	<.001	3	4
UCEC	WIPF1 →	+1.019	+0.396	<.001	<.001	3	4
CCRCC	APOC1 →	+1.203	+0.284	<.001	<.001	3	4
CCRCC	GPNMB →	+1.482	+0.412	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,682 associations by consensus.

PLBD2 vs TLR8 — UCEC

Explore this scatter interactively →