PLBD2

Across TCGA cell cohorts, PLBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,698 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLBD2-associated GO terms across cancer lineages are Viral process, Biological process involved in symbiotic interaction, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with PLBD2 in more than 17 cancer types. Because this analysis shows association rather than direction, both PLBD2-to-partner and partner-to-PLBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by PLBD2-low versus PLBD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLBD2→partner) and Y-score (partner→PLBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral process →	+0.083	+1.015	<.001	<.001	3	18
BONE	Biological process involved in symbiotic interaction →	+0.099	+1.020	<.001	<.001	3	18
BONE	Multi-pass transmembrane protein insertion into ER membrane →	+0.128	+1.228	.001	.004	2	18
STOMACH	Viral life cycle →	+0.116	+1.081	<.001	<.001	3	16
BONE	Actin filament depolymerization →	+0.225	+1.313	<.001	<.001	3	16
BREAST	Symbiont entry into host →	+0.134	+1.024	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,698 associations by consensus.

Viral process by PLBD2 expression — BONE

Explore this box plot interactively →