PLBD1

Across TCGA cell cohorts, PLBD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,768 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLBD1-associated GO terms across cancer lineages are Protein catabolic process in the vacuole, Lysosomal protein catabolic process, and Negative regulation of potassium ion transmembrane transporter activity. Each is linked with PLBD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLBD1-to-partner and partner-to-PLBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process in the vacuole grouped by PLBD1-low versus PLBD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLBD1→partner) and Y-score (partner→PLBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein catabolic process in the vacuole →	+0.108	+2.329	.003	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Lysosomal protein catabolic process →	+0.129	+1.645	<.001	.004	3	6
BONE	Negative regulation of potassium ion transmembrane transporter activity →	-1.184	-1.247	<.001	<.001	3	6
BONE	Negative regulation of voltage-gated potassium channel activity →	-1.184	-1.247	<.001	<.001	3	6
BONE	Endoplasmic reticulum mannose trimming →	+0.118	+1.176	<.001	.002	2	6
LUNG_SCLC	SNARE complex disassembly →	-0.209	-3.156	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,768 associations by consensus.

Protein catabolic process in the vacuole by PLBD1 expression — STOMACH

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