PLB1

Across TCGA patient cohorts, PLB1 protein abundance is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. OV shows the largest number of these associations.

The most reproducible PLB1-associated genes across cancer lineages are ABHD17B, TRIM16L, and ELF2. Each is linked with PLB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLB1-to-partner and partner-to-PLB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLB1 versus ABHD17B in OV, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLB1→partner) and Y-score (partner→PLB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ABHD17B →	-0.553	-0.450	.008	.001	3	1
OV	TRIM16L →	-0.543	-0.473	.003	.008	3	1
OV	ELF2 →	-0.570	-0.389	.001	.008	3	1
OV	FZD10 →	-1.503	-0.532	.003	.006	3	1
OV	GADD45G →	-1.207	-0.431	.006	.003	3	1
OV	UCK1 →	-0.817	-0.392	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

PLB1 vs ABHD17B — OV

Explore this scatter interactively →