Across TCGA cell cohorts, PLAC9 mutation is significantly associated with the mutation status of many other genes, with 966 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PLAC9-associated genes across cancer lineages are DDT, GGT5, and NUGGC. Each is linked with PLAC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLAC9-to-partner and partner-to-PLAC9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAC9→partner) and Y-score (partner→PLAC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DDT →	+5.415	+5.415	.004	.004	1	1
OVARY	GGT5 →	+4.415	+4.977	.007	.007	1	1
OVARY	NUGGC →	+4.415	+4.977	.007	.007	1	1
OVARY	LIN54 →	+5.415	+5.415	.004	.004	1	1
OVARY	ZNF724 →	+4.415	+4.977	.007	.007	1	1
OVARY	SEMA4A →	+5.415	+5.415	.004	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 966 associations by consensus.

Exploration

PLAC9 survival (RNA) · tumor vs normal (RNA) · all PLAC9 data types