PLAC1

Across TCGA cell cohorts, PLAC1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLAC1-associated genes across cancer lineages are ZNF831 and CENPVL1. Each is linked with PLAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLAC1-to-partner and partner-to-PLAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF831 grouped by PLAC1-low versus PLAC1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAC1→partner) and Y-score (partner→PLAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF831 →	+0.013	+3.688	<.001	.002	3	1
LARGE_INTESTINE	CENPVL1 →	+0.150	+3.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ZNF831 by PLAC1 expression — LARGE_INTESTINE

Explore this box plot interactively →