PLAAT2

Across TCGA patient cohorts, PLAAT2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PLAAT2-associated genes across cancer lineages are Megakaryocytes and Adipocytes. Each is linked with PLAAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLAAT2-to-partner and partner-to-PLAAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocytes grouped by PLAAT2-low versus PLAAT2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAAT2→partner) and Y-score (partner→PLAAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Megakaryocytes →	+0.040	+2.843	.002	.049	3	1
UCEC	Adipocytes →	+0.036	+2.851	.004	.044	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Megakaryocytes by PLAAT2 expression — SKCM

Explore this box plot interactively →